Ortega is known for her gothic roles, having starred in 2022 horror film X and hit Netflix show Wednesday, based on a character from The Addams Family, created by cartoonist Charles Addams.
The 21-year-old arrived at the event on Friday wearing a dark purple suit dress with pointed shoulders and red detailing that matched her tights.
She paired the look with cherry red high heels and red sunglasses.
The Scream actress, who plays Astrid Deetz in the film, posed for photos alongside her co-stars on a set that was decorated with gravestones.
Also at the press call at One Marylebone in central London, Ryder, who has starred in Tim Burton film Edward Scissorhands and Netflix series Stranger Things, wore a dark grey ensemble to the event.
The 52-year-old, who plays Lydia Deetz in the movie, paired the matching jacket and skirt with black combat boots, a smoky eye and an updo.
Lydia Deetz has her life turned upside down when her rebellious teenage daughter, Astrid, discovers the mysterious model of the town in the attic and the portal to the afterlife is accidentally opened.
With trouble brewing in both realms, it is only a matter of time until someone says Beetlejuice’s name three times, and the mischievous demon returns to unleash his very own brand of mayhem.
Following its premiere on Wednesday, the film received a standing ovation.